In order to comply with the trend of intelligentization and informationization of freeze dryers, some experts have carried out data cloud transformation on freeze dryers. The main steps of the whole project are the project architecture; the hardware preparation work required for system development, including the hardware required for system development, the hardware connection methods; the construction of the operating environment; the construction of the development environment; the PLC communication protocol; data preparation; Including the serial port expression string of the development board and the data acquisition program of the freeze dryer.
In this project, the expert used the ARM development board to replace the traditional PC. Compared with the traditional PC system architecture, the ARM development board has many advantages, such as small size, low power consumption, low heat generation, stable operating system, and easy installation. You can use the universal ARM development board that can install the Linux operating system and has its own RS232/485 serial port.
This project is not only a product of the era of intelligent medical equipment, but also provides a reference for the information transformation of various other types of pharmaceutical equipment. More importantly, the data collection process has stored all the operating data of pharmaceutical equipment in the cloud database in the cloud, which is of great significance for the future statistics of various big data and the traceability of drug quality.
In addition to the development of compliance with the intelligent development of lyophilizers, and in accordance with the development of regulatory requirements, many freeze dryer companies have further explored. Taking the complete detection method of the lyophilizer filter core as an example, most of the sterile preparations produced by the lyophilizer are non-terminally sterilized sterile preparations. For non-terminally sterilized sterile preparations, the sterility assurance of the preparation relies primarily on sterility control during the production process, while the sterile preparations are controlled during the production process prior to entering the lyophilizer, each filter element Integrity plays a key role.
